DNA to mRNA to protein

Severo Ochoa

The way in which the genetic information stored in DNA is transmitted to the protein making machiney of the cell, so that a specific nucleotide sequence in DNA gives rise to a unique amino acid sequence in the polypeptide chains of proteins, is now fairly well understood. RNA participates in this process as a messenger between the DNA and the protein. DNA directs the synthesis of messenger RNA (mRNA) and this in turn directs the synthesis of protein.

Fonte: Ocho, S. 1975. Protein synthesis and the genetic code. Proceedings of the Royal Institution of Great Britain 48: 63-86.